Systemic lupus erythematosus

From Descipher Health

Description:

Table of contents

1 Synonyms 2 Cause 3 Population Distribution 4 Effects 5 Symptoms 6 Signs 7 Diagnostic Tests 8 Differential Diagnosis 9 Treatment 10 Expected Outcome 11 Prevention 12 Medical References 13 External Links

Synonyms

disseminated lupus erythematosus, Libman-Sacks disease, SLE

Cause

An autoimmune disorder of unknown cause. It may affect any organ.

Population Distribution

Effects

Symptoms

• butterfly rash
• fatigue
• fever
• hair loss
• joint pain
• joint swelling
• muscle pain
• painless mouth ulcers
• painless nose ulcers
• photosensitivity

Signs

Diagnostic Tests

• blood tests

SM/RNP Anibody

SM/RNP AB Interprstation

3.00 ( H) Positive (A) <OR=1.00 Negative

RNP Antibodies are found in mixed connective tissue Disease (MCTD, SLE RA Sjogren's Syndrome, Progressive systemic sclerosis,and drug induced LE.the presence ofRNP Antibodies in the absence of SM and DNA Antibodies suggests MCTD,while the absence of RNP usually rules out MCTD.

Reference range: Negative: Less than or equal to 1.00 index Positive: greater than 1.00 index

Differential Diagnosis

Treatment

Expected Outcome

Prevention

Medical References

External Links

• American College of Rheumatology (http://rheumatology.org)

• Lupus Foundation of America (http://lupus.org)

• National Institute of Arthritis and Musculoskeletal and Skin Diseases (http://www.niams.nih.gov)